- To be identified as the global leader of sourcing and procurement services and as a reliable supplier of products to the Life Sciences and Fine Chemicals Industries.
- To advance the business of our customers and suppliers while progressing quality of life through their products.
- To be at the forefront of developing technology that brings value to our customers.
- To bridge customers’ needs and supplier capabilities while addressing all environmental safety and regulatory compliance requirements.
- To accelerate drug and chemical development programs to commercialization through the use of our global suppliers.
Products
Examples of Reaction Capabilities
01/28/2011Austin Chemical Launches Revised Website
02/18/2011Products
Services Offered
- Bioavailability/Bioequivalence Studies
- Clinical Trials
- Bio-analytical Services
- Preclinical Studies
- Analytical Services
- Clinical Data Management
- Diagnostic Services
- Clinical Research Testing
Related posts
Mission Statement;
Overview
Austin Chemical Company, Inc. (ACCI) celebrates its fifth decade in business as a representative and partner company. Founded in 1976 as a Sales and Marketing company offering ingredients, raw materials, and intermediates to Life Sciences Companies; ACCI has grown substantially over the years to include PR&D, CDMO/CMO services, and technical solutions. Additionally, we are pleased to support Fine Chemical Companies focusing on, but not limited to, the C.A.S.E. marketplace.
ACCI representations have continually expanded; including companies based in Japan (70’s/80’s), Europe and China (80’s), and India (90’s). Austin formally began its partnering activities in 2012 (Netherlands, Switzerland, USA) creating a solid position in technical support services (PR&D) and products supply addressing customer developmental program needs.
ACCI was the first company to offer Sourcing and Procurement services (late 1980’s) with its first contractual agreement as an asset extension to DOW beginning in 1992. We have expanded our services to include a “Tail End Sourcing Support Program” (2018) which addresses specific customer commercial needs often not routinely addressed due to direct purchasing personnel prioritization programs.
ACCI’s fee-based Market Investigation Program was introduced in 2008 and supports both customer and supplier needs. A subset of additional offerings resulted soon thereafter; including Supply Chain Risk Analysis, Due Diligence, and Confidential Sourcing.
ACCI has created flexible customer programs that address both short and long term USA based warehousing needs. We also support Supplier Contractual Distribution activities and requirements.
ACCI has an active Logistics program assisting with the global movement of products on behalf of customers and suppliers.
Discovery to Commercial Scale
Development Services
Exclusive Bitter Receptors Screening Service
- Determine the potency and efficacy drugs, drug products, and reference compounds against the 22 human TAS2R bitterness receptors
- Host cells have been constructed that contain a clone of the receptor, the coupling G-protein, and a fluorescent reporter.
- Binding of a bitter compound to a TAS2R leads to activation of the signal transduction pathway and an increase in fluorescence, enabling generation of dose-response data.
- Available to test per API per receptor for response as well as testing against proprietary antagonists
Relevance in Current Environment
The future of manufacturing is efficiency, automation and enabling technologies (Industry 4.0, Smart Manufacturing, IIOT, etc.)
Automatic Continuous Online Monitoring of Polymerization Reactions for Lab and Pilot Plant Scale Reactions
APMT’s proprietary ACOMP platform solution is a completely automated means of characterizing polymers during synthesis or other processing steps.
ACOMP allows for tighter control of processes resulting in:
Automatic Continuous Online Monitoring of Polymerization Reactions for Industrial Processes
APMT
APMT Profile
- Operations began 2013, New Orleans, LA after spin-out from Tulane University
- Foundation of 10 issued patents, 25 pending and over $20M in R&D investment
- Presently operating out of 6,700 sq. ft. facility
- Core team of people (R&D, engineering, manufacturing, field service, operations)
- Technical Advisory Board (TAB) of five world experts in polymers and biotechnology
- Focused on developing IIOT, hardware/software/data products
Relevance in Current Environment
The future of manufacturing is efficiency, automation and enabling technologies (Industry 4.0, Smart Manufacturing, IIOT, etc.)
Automatic Continuous Online Monitoring of Polymerization Reactions for Lab and Pilot Plant Scale Reactions
APMT’s proprietary ACOMP platform solution is a completely automated means of characterizing polymers during synthesis or other processing steps.
ACOMP allows for tighter control of processes resulting in:
Automatic Continuous Online Monitoring of Polymerization Reactions for Industrial Processes
Trending
| Brimonidine, cas# 70359-46-5 |
API reference material |
| Potassium peroxymonosulfate, | Versatile oxidizing agent |
| Naftifine # 65472-88-0 | API reference material |
| N-Octylphosphonic acid, cas# 4724-48-5 |
Surface coatings agent, micro/ nanotechnology |
| LiHMDS<span style=, cas# 4039-32-1 |
Organic base, polymerization acceleration |
| Squalene, cas# 111-02-4 | Cosmetics, nutritional |
| Lisinopril<span style=, cas# 83915-83-7 |
API reference material |
| Fosinopril<span style=, cas# 98048-97-6 |
API reference material |
| Candesartan, cas# 139481-59-7 |
API reference material |
| Enalapril<span style=, cas# 75847-73-3 |
API reference material |
| methacrylate, cas# 3063-94-4 | Monomer |
| ‘font-size:11.0pt;”>-4-Hydroxy-D-proline, cas# 3398-22-9 |
Chiral building block |
| Hydroxy ethyl starch, cas# 9005-27-0 | Nonionic starch derivative, blood volume expander |
| TCEP, cas# 51805-45-9 | Reducing agent, peptide disulfide bonds |
| Methane Sulfonic acid, cas# 303-81-1 | Organic acid, pharmaceutical grade |
| Ravecarb Polycarbonate Diols | Precursor for high performance polyurethanes |
| Novobiocin acid, cas# 303-81-1 |
API reference material |
| Vecuronium Bromide, cas# 50587-95-6 |
API reference material |
| Ishikawa’s reagent, cas# 309-88-6 | Fuorination reagent |
| Iodine monochloride, cas# 7790-99-0 |
Organic synthesis reagent |
| Tartaric acid, cas# 87-69-4 | Chiral molecule, salt |
| Cyclohexanecarbonyl chloride, cas# 2719-27-9 |
Organic synthesis |
| (2S)-(+)-Glycidyl tosylate, cas# 70987-78-9 | Chiral synthesis |
| 3,4 Di Methoxy aniline, cas# 6315-89-5 |
Amine building block |
Formulation Offerings
Solid Dosage
Annual Capacity
- Tablets – 2 Billion (expandable to 3 Billion)
- Capsules – 300 Million (expandable to 600 Million)
Production Capacity
- Five Granulation Areas – 2000 Kilos per shift
- Eight Compression Areas – 10 Million per shift
- Five Coating Areas – Sugar, Film and Enteric,Aqueous and Solvent-based
- Two Encapsulation Areas – 2 Million per shift
Batch Size
- 10 – 30 Kilos in pilot scale
- 80 – 480 Kilos in production plant
- Blending to 1000 Kgs
Packaging
- Blister – PVC, PVC/PVdC, Alu/Alu • Bottle • Bulk
- Primary packaging area air filtered and conditioned to 0.3 μ
- Individual and dedicated air handling units with pressure cascade
- Purified water by Ultrafiltration, Reverse Osmosis and Electro-deionization to BP/EP/USP standards
- Ability to handle manufacture and packaging of moisture-sensitive products (<20% RH)
Regulatory Status
- WHO-GMP certified
- MHRA and TGA approved
- No beta-lactams, biologicals, cytotoxics,or hormones handled on site
- FDA inspection planned for mid 2011
- Ophthalmic unit planned for Q4, 2012
Solid Dosage
Forms
- Injectibles (Human and Veterinary)
- Ophthalmics
- Ear Drops
- Nasal Drops
Presentations / Annual Capacities
- Liquid Vials – 43 million
- Lyopholized Vials – 3 million
- Prefilled Syringes (0.1 to 5 ml) – 32 million
- Ampoules – 23 million
- Three-piece dropper bottles (0.5 to 10 ml) 16 million
Regulatory Status
- WHO-GMP certified
- FDA inspected
- TGA and MHRA audits planned
- Oncologic unit planned for Mid 2011
Typical Procedures Include
- HPLC, UV/Vis Spectrophotometry, Particulate Analysis, Endotoxin Analysis, FTIR Spectroscopy, Sterility Testing
Particle Engineering
Research, Development and Commercial Scale Supply
Pre-clinical Solubility & Bioavailability Enhancement
- Screening method: Quenching and Film Casting
- Processing Solid Dispersions: Spray Drying, Melt Extrusion, Spray Congealing and Electro Spinning
- Analytical Solid State Testing: mDSC, XRPD, FTIR
- Stability Testing at different Temperatures and Relative Humidities
- In Vitro Dissolution Testing
- Final Dosage as powder, tablet or capsule, by using different formulation technologies
- High Shear Wet Granulation
- Fluid Bed-Dryer-Coater-Granulator
- Vacuum Dryer
- Extruder
- Spheroniser
- Tablet Press
- Tablet/Capsule Coater
- Capsule Filling
Micronization
- Grams to Tons
- Over 200 commercial products handled annually
- Experience with over 1,000 different products
- Containment systems up to 0.1 μg/m3
- Jet-MCA® (Mechano Chemical Activation) for API-carrier composites
- Capacity greater than 1,000 MT/year
Formulation Spray Drying Solutions
- Grams to Tons
- Ideal for Temperature Sensitive Products
- Aqueous and Solvent systems
- Containment systems up to 1 μg/m3
- Solid Dispersions
- Amorphous Powders
- Powders for Inhalation
- Lipo-Technology
Bulk Spray Drying Solutions
- Solid dispersion technology
- Improvement of API properties
- Oily API to Powder
- Orally disintegrating tablet system – F-MELT® system
- Capacity greater than 2,000 MT/year
Nano-emulsions
Examples of past successes:
- Fish Oil
- Conjugated Linoleic Acid
- Boswellia Serrata
Nanoparticles
- with Supercritical Fluid Precipitations
- with Nanonizer®
- with HGCP® technology
Other Services
- Roll Compaction
- Briquetting
- Blending
- Mechanical classification
- Mechanical pulverization
ChemConnection
ABOUT US
ChemConnection is an innovative, award-winning company with a focus on the development and GMP production of innovative nanomedicines and active pharmaceutical ingredients. ChemConnection is privately owned and is located at the Pivot Park in Oss, the Netherlands. The company became operational in 2012 and evolved from the Organon/MSD early phase chemical development team. Currently, the company employs 35 FTE including chemical development, analytical development and validation, and GMP manufacturing. ChemConnections customers are located in Europe, USA, and Japan.
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Due Diligence Asia
- Fixed monthly fee (based upon estimated number of inquiries) plus all additional costs (i.e.: material, shipping, import, delivery)
- Minimum period of 12 months with termination without cause upon 90 days notice
- Monthly fee payable at start of each month. Itemized additional costs (materials, clearance, etc) to be invoiced at month end
- Confidential Sourcing based on Customer’s preference
- Austin responsible for Hazmat compliance, shipping, import, logistics and delivery
- Austin will provide the best source(s) specific to quality, availability and price
- Inquiries to be processed within 24 hours of receipt
- Response time for commercial items:
- 5 days – US, Europe and Japan
- 5-10 days – Southeast Asia
- Advise non-commercially available items: 48 hours
- Austin, through our partner network, shall attempt to develop custom sources for products not offered commercially
- Custom synthesis: Possible sources identified within 5 days
- Customers to advise purchase decision for ordering / updating of suppliers
- Customers to provide periodic updates on the status of the projects for updating of suppliers
Austin Offers
- Over 30 years of sourcing experience
- Database of over 100,000 compounds
- Global network (USA, Asia, Europe, Japan)
- Access to diverse manufacturing capabilities
- Due diligence by global personnel
- Onsite personnel in Asia
- Dedicated sourcing personnel
- Proven systems in place
- Supply chain management including HazMat and Logistics
- Dedicated customer service to support needs
Sourcing and Procurement Deliverables
- Pricing
- Availability
- Specifications
- Manufacturer information – name, supply capabilities, etc
- Procurement services
- Custom clearance
- Duty payment
- Delivery
- Logistics support
- HazMat support
Austin’s Sourcing Solutions
zuChem
Natural Process to Add Value & Advance Human Health & Nutrition
zuChem is a leading producer of unique sugars for human health and nutrition.
zuChem develops proprietary process technologies for the manufacture of carbohydrates in the food, specialty and fine chemical markets. zuChem researchers have a proven track record in developing and implementing scalable, industrial quality processes.
zuChem Inc. and Austin Chemical Company have formed an alliance for Austin Chemical to market and sell zuChem-produced rare sugars produced under its zuCarb™ product line worldwide. Austin represents both zuChem’s product and custom synthesis service offerings to the fine chemicals and pharmaceuticals industry.
zuCarb™ Research Carbohydrates & Intermediates
Monosaccharides
Rare/modified sugars, phosphorylated sugars, activated sugars
Pharmaceutical products that incorporate glycochemicals have tremendous therapeutic potential. However, pharmaceutical research with glycochemicals has been limited, at least in part, due to the fact that rare and modified glycochemical building blocks needed to research and manufacture these new drug candidates is difficult and expensive. zuChem’s proprietary technologies and uniquely experienced staff can provide many of these rare sugars as you need them and can develop the technologies and process to create one-of-a-kind solutions for you.
Austin Chemical Shanghai
Austin Shanghai is an independent functional group offering dedicated sourcing, logistics and supporting services to Austin related projects.
Our services include due diligence, supply chain risk analysis, sourcing, procurement and market investigation, etc.)
China is the best source for basic chemical starting materials and intermediates with over thousands of chemical factories involved in chlorination, fluorination, nitration, oxidation, fermentation, boron chemistry, etc.
Hundreds of R&D companies are available for CRO service and small volume building blocks for research and discovery.
There are also hundreds of experienced pharmaceutical manufactories offering cGMP level key intermediates for pharmaceutical customers that requires more sophisticated chemistry, process optimization, etc. in large scale for lower cost.
Austin Shanghai has more than 24 years of experiences in China and we have established good relationship with manufacturers in help them to overcome the EHS hurdles and customer service issues that stopped them from being accepted by western customers.
Austin Chemical India
Austin Chemical India, based in Chennai, the capital of Tamil Nadu, fully supports your needs for Development and Commercial supply materials. We provide Starting materials to Finished dosage formulated product to Global Fine Chemical and Life Science companies.
Our sourcing activity is tailored to meet customer needs offering complete solutions by identifying & qualifying suppliers offering consistent quality and reliability from facilities complying to international standards.
Austin India facilitates pre inspection of facilities through due diligence audits to acceptance of EHS, QMS, cGMP & other regulatory systems guidelines.
Our detailed due diligence helps minimize risk factors associated to supplier acceptability and reliability concerns offering potential for long term supplier relationships.
Qualified in Hazmat evaluation we assure appropriate packaging and labeling that is in compliance with IATA/IMDG requirements for proper transport by air & sea.
With India being a leading supplier of Pharma products & services to the world, it is also big market for product/raw material consumption. Austin India using our vast network often conducts Market Investigations for products that could be likely sold into or out of India.
Nagarajan M.N./ACCI
Austin Chemical India
F1.,VCK Royal Gardens, Plot no. 15,
Surendra Nagar 6th St.,
Adambakkam, Chennai – 600088
Phone :+91 760 487 7953
Fax +91-44-4212 3743
Email : mnraj@austinchemical.com
Website www.austinchemical.com
Products, Technologies, and Services notable to India include:
| Chlorination | Bromination |
| Chlorosulfonation | Nitration |
| Propargyl | Indole |
| Azaindole | Boron |
| Thiophene | & Chiral chemistry compounds. |
Austin India contacts new suppliers on a continuing basis every week growing our experience and knowledge to over 150 companies. Many have been visited and or audited by Austin.
Name |
Category |
| Vegesna Laboratories Private Limited | Toll Manufacturing Company |
| Symphony Life Sciences Pvt Ltd | Custom Synthesis |
| Sreeni Labs Private Limited | Custom Synthesis |
| Ci Venti Chem India Private Ltd | Custom Synthesis |
| Innovassynth Technologies | CRAMS |
| Alchem Synthon Pvt. Ltd. | Custom Synthesis Propargyl & Complex Thiophene |
| Alchem International | Natural product extracts |
| Centaur Pharmaceuticals Pvt. Ltd. | API And Formulations |
| Aarti Drugs Ltd | Chlorination and Chlorosulfonation on Commercial Scales. |
| Adani Pharmachem Pvt. Ltd. | Iodine, Piperazine And Citrate Derivativies. |
…..and list goes on. Please note that the above list are in addition to our regular API, intermediate suppliers like the Lupin, Hetero, Divis, Wochhardt, IPCA, Cipla, Unimark Remedies, Mega Fine, MSN Labs, Hikal and others.
CBB
Chemical Biological Bulk Manufacturing Network and Services S.A
CBB is an independent functional group located in Lugano, Switzerland offering dedicated global sourcing, logistics and supporting services to its customers. Services include but are not limited to due diligence, supply chain risk analysis, sourcing, procurement, and market investigations.
Carlo Cantabene
President
carlo@cbb-net-sa.com
Dr. Hansjörg Jakubetz
Partner
hj@cbb-net-sa.com
D. Ph. Schneider
Partner
ds@cbb-net-sa.com
Office
Via Trevano 2
CH-6900 Lugano Switzerland
Phone +41 91 921 10 32
Syncom
Excellence in designing Chemistry and delivering Molecules
For more than 25 years, Syncom has been supporting the pharma and biotech industry medicinal chemistry and PR&D needs with world class services. Syncom operates a state of the art 45.000 ft2 facility in Groningen, The Netherlands. A team of over 90 experienced chemists – of whom 60% has a PhD degree – is available to support your projects and tackle complex chemical problems. If you are looking for a flexible, customer oriented chemistry CRO with outstanding scientific skills Syncom is the place to go.
Key activities include:
Medicinal chemistry, hit to lead optimization programs, library synthesis
Process R&D, route scouting and development, winner Pfizer Process R&D innovation award in 2011
Leading supplier of reference standards, metabolites and impurities. Over 1500 unique and complex metabolites, standards and impurities synthesized
Custom synthesis up to 50 L scale
World leader in chiral chemistry. Outstanding skills in chiral resolution and inventor of the “Dutch Resolution”
Capabilities to deal with difficult substance classes
– Vitamin D derivatives
– Carbohydrates
– Steroids
– Dedicated and segregated beta lactam lab
Consulting Services
Austin can cost-effectively speed product time to market, supporting the following:
- API Manufacturing
- Drug Product Formulation
- Quality and Regulatory Compliance
- Growth Financing
- Business Relocation
- Product or Business Valuation
- Acquisition Due Diligence
- Partnering and Licensing Strategies
Expert staffing and consulting is available with fee consideration to immediately close one-time knowledge and asset gaps, enabling your firm to meet strategic goals and keep its personnel focused on primary business objectives.
Distribution Services
Austin Chemical Company, Inc. provides distribution services for foreign manufacturers, which encompass import/export, storage, shipping, invoicing, and payment collection. The customer’s ability to draw upon a continuous supply source helps to establish a manufacturer’s presence within the marketplace through our services. Austin is now offering its 30+ years of experience to those companies that only need the “distribution” part of our activity.
- Serving the Health Sciences and Chemical Industries for over 30+ years
- Fee structure based on volume or value of products
- Focus to meeting our suppliers’ or customers’ requirements and expectations
- Singular point of contact for orders – one phone call
- Optional sales and marketing support services
- Optional invoicing and collection services
Warehousing
- Locations in Illinois and New Jersey
- Pharmaceutical, nutraceutical, and food grade ingredients
- Specialty handling of hazardous materials
- Separate secure storage of chemical and hazardous materials
Distribution Packaging
- Labeling
- Bar coding
- Palletizing
- Shrink wrapping
- Lot management
- Lot specific shipments
Supply Chain Risk Analysis
Austin’s Supply Chain Risk Analysis service product identifies and minimizes risks associated to:
Procurement
- Assurance of cost competitiveness
- Proposal for cost-cutting strategies
- Implementation cost vs. benefit analysis
- Focus on key, high-value, single-sourced, and/or “high maintenance items”
Suppliers
- Assessing security of current supply chain
- Identification of alternate suppliers
Materials Management and Transportation
- Order quantities and patterns
- Lead-time and inventory planning
- Quality and dispensing costs
Reasons to Outsource your Supply Chain Risk Analysis with Austin Chemical:
- Expert knowledge of best practices
- Global service and supply options
- Programs are offered on a fixed-fee basis
> Tiered fee schedule, based on scope of project
> Typically 3 or 5 day, on-site execution
Global Logistics Overview
Austin provides logistical support services to its customers and suppliers by moving products globally to support internal and external needs. Austin will broker delivery of raw materials and value-added products to and from the US and SouthEast Asia.
- Fee structure based on value or volume of products Focused to meeting our customers’ and suppliers’ requirements and expectations
- Singular point of contact for orders – one phone call
- Freight consolidation and optimization
- FCL and LTL capability Interstate, intrastate, and international distribution capabilities
- Extensive relationships with brokers, shippers, freight forwarders, and U.S. Customs and Border Protection
- Hazardous material handling certification / DOT & UN compliance JIT inventory management
Global Logistics – China and India Overview
- Staff of five in Shanghai (20 years); one in Chennai (9 years); one in Korea
- Region-specific knowledge of products, providers, and service industries
- Site and Quality Systems prequalification / supplier due diligence
- CRO/CMO manufacturers with known capabilities
- Emerging technology provider assessment
- Knowledge of local customs
- Supply Chain Management
- Hosting of customer visits
- Factory visits
- Materials Hazard classification
- Packaging selection
- Export logistics
- Raw material importation
- Discovery material export
- Typical timeline is 10 days from consolidation of products to clearance in the US
- Austin MSDS preparation and submission to authorities for Hazmat classification
- Packaging in accordance with international transportation regulations
- Preparation of commercial invoice reflecting full value of products and submission to Chinese customs for export clearance
Market Investigation
Austin provides detailed product and service market analysis (North America/United States) information.
Investigation can be expanded to markets outside of the United States.
-
Fee structure based on scope of investigation
-
Market entry program development services
-
Singular point of contact
-
Optional sales and marketing support services
Sourcing & Procurement
- Fixed monthly fee (based upon estimated number of inquiries) plus all additional costs (i.e.: material, shipping, import, delivery)
- Minimum period of 12 months with termination without cause upon 90 days notice
- Monthly fee payable at start of each month. Itemized additional costs (materials, clearance, etc) to be invoiced at month end
- Confidential Sourcing based on Customer’s preference
- Austin responsible for Hazmat compliance, shipping, import, logistics and delivery
- Austin will provide the best source(s) specific to quality, availability and price
- Inquiries to be processed within 24 hours of receipt
- Response time for commercial items:
- 5 days – US, Europe and Japan
- 5-10 days – Southeast Asia
- Advise non-commercially available items: 48 hours
- Austin, through our partner network, shall attempt to develop custom sources for products not offered commercially
- Custom synthesis: Possible sources identified within 5 days
- Customers to advise purchase decision for ordering / updating of suppliers
- Customers to provide periodic updates on the status of the projects for updating of suppliers
Austin Offers
- Over 30 years of sourcing experience
- Database of over 100,000 compounds
- Global network (USA, Asia, Europe, Japan)
- Access to diverse manufacturing capabilities
- Due diligence by global personnel
- Onsite personnel in Asia
- Dedicated sourcing personnel
- Proven systems in place
- Supply chain management including HazMat and Logistics
- Dedicated customer service to support needs
Sourcing and Procurement Deliverables
- Pricing
- Availability
- Specifications
- Manufacturer information – name, supply capabilities, etc
- Procurement services
- Custom clearance
- Duty payment
- Delivery
- Logistics support
- HazMat support
Austin’s Sourcing Solutions
Sales & Marketing
Austin works as an asset extension of a supplier’s global marketing strategy on a fixed fee or commission basis, establishing field sales presence at significantly lower cost.
Austin provides direct-to-end-user Market Introduction Services and Representation for product manufacturers and service providers.
We provide industry-leading global sourcing and procurement services to more than 650 North American Life Sciences and Specialty Fine Chemicals companies.